Fatboy-

What kind of issues are you having? Accuracy? Function?

If you are not having success with 8208XBR or Varget, then you need to look at other variables.

Check your powder drops to be sure that they are consistent. 8208 flows really well for me.

Sort brass by headstamp. Do you put a crimp on your finished round? I find that a light crimp really helps with a semi auto.